Original Article

Hidradenitis Suppurativa: Current Trends of Treatment in Bangladesh

  • Afroza Jesmin,1 Muhammad Munir Rashid,2 Md. Abdul Hamid,3 Abu Jafar Md Shahidul Hoq,4 Kaniz Shahali Reza Snigdha,3 Abu Reza Sayem Ahamed,3 AKM Mahbubul Alam,3 Ikbal Ahmed,3 Towhida Noor,5 Farhana Nishat,6 Abu Hena Chowdhury,7 Md. Zulfiqur Hossain Khan8

  • Volume 3, Issue 2, Page No: 50-57

Author Details

1. Junior consultant, Department of Dermatology & Venereology, Mugda Medical College Hospital, Dhaka, Bangladesh. E-mail: dr.afrozajesmin@gmail.com
2. Professor, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
3. Assistant Professor, Department of Dermatology & Venereology, Mugda Medical College Hospital, Dhaka, Bangladesh.
4. Associate Professor, Department of Dermatology & Venereology, Mugda Medical College Hospital, Dhaka, Bangladesh.
5. Consultant Dermatologist, Matador Diagnostic & Wellness Center, Dhaka, Bangladesh.
6. Consultant, Department of Dermatology &Venereology, Dhaka Medical College Hospital, Dhaka, Bangladesh.
7. Associate Professor, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
8. Professor, Department of Dermatology & Venereology, Mugda Medical College Hospital, Dhaka, Bangladesh.


Abstract

Background: Hidradenitis suppurativa (HS) is a chronic, recurrent, debilitating dermatosis. Management of HS remains a challenge owing to lack of a curative medical treatment, potential resistance of recommended antibiotics and higher cost of biologics.

Objectives: The study aimed to assess the current trends in treatment patterns of Hidradenitis suppurativa in Bangladesh.

Methods: The cross-sectional study was conducted between January 2023 and March 2023 among 76 dermatologists from all over Bangladesh. A pretested, semi-structured questionnaire containing 13 questions targeted mainly prescribing patterns based on their regular clinical practices. The data has been collected through both online and in-person interviews.

Results: The study found that topical+systemic antibiotics were the most frequently used treatment modality for HS in all severity groups. Doxycycline was the most preferred systemic antibiotic, followed by Clindamycin. Most of the dermatologists (79%) did not prescribe the combination therapy of clindamycin + rifampicin as a reason for drug resistance (51.7%) and unavailability (46.6%). However,46% prioritized isotretinoin as non-antibiotic treatment and 78% have never given biologics for HS treatment. When it comes to surgical intervention, almost half (43.4%) of the dermatologists never performed any surgical procedure in clinical practices and they referred the patients to a plastic surgeon (30.2%). The study explored the challenges of HS treatment in Bangladesh, including the chronic nature of the disease (76.3%) and patients not compliant with prescribed treatment (52.6%) as challenges in treating HS treatment.

Conclusion: Identifying and addressing barriers to achieving expertise in the treatment of HS can help provide access to high-quality care for patients with HS.

Keyword: Hidradenitis Suppurativa, combination therapy, non-antibiotic therapy, Biologics. 

Keywords: Hidradenitis Suppurativa, Combination Therapy, Non-Antibioyic Therapy, Biologic

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